Found 11 matching trials
A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects PHASE1 This study will be a 2-part, open-label, single-center relative bioavailabi...
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Assessing a ctDNA and PET-oriented Therapy in Patients With DLBCL A Multicenter, Open-label, Phase II Trial. PHASE2 Within this exploratory multicohort phase II trial, SAKK aims to evaluate a...
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Active Not Recruiting
Location
Ospedale Papa Giovanni XXIII
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A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma PHASE2 This phase II trial compares three chemotherapy regimens consisting of bend...
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Active Not Recruiting
Location
Anchorage Associates in Radiation Medicine
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A Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL. PHASE3 This is a global, multicenter, randomized, open-label, Phase III confirmato...
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The First Affiliated Hospital of Bengbu Medical College
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A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001) PHASE1 This study aims to evaluate the safety, tolerability, pharmacodynamic, and ...
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Active Not Recruiting
Location
Mayo Clinic Hospital ( Site 0140)
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APR-246 in Combination With Acalabrutinib or Venetoclax Based Therapy in Subjects With R/R Non Hodgkin Lymphomas (NHL) PHASE1 Study to determine the preliminary safety, tolerability, and pharmacokineti...
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Massachusetts General Hospital
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A Study to Evaluate the Effect of ACP-196 on the Heart Rate-corrected QT Interval in Healthy Adult Participants PHASE1 This study is to evaluate the effects of single therapeutic and supratherap...
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Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma PHASE2 This phase II trial studies the effects of acalabrutinib, umbralisib, and u...
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Active Not Recruiting
Location
City of Hope Medical Center
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A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole PHASE1 This Phase 1 study is being conducted to support the clinical development o...
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Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma PHASE2 This phase II trial investigates how well modified VR-CAP (bortezomib, ritu...
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Active Not Recruiting
Location
Mount Sinai Hospital
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